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IsoWalk

Dr. Benjamin DH Gordon’s research team is currently conducting a research study called “IsoWalk”. Limited data suggest that combining multiple modes of exercise may amplify the BP-lowering effect through independent physiological mechanisms. Specifically, isometric exercise training (IET) appears to lower BP through different mechanisms than traditional aerobic exercise (e.g., walking). However, gaining a greater understanding of the feasibility and BP-lowering benefits of an exercise regimen combining walking+IET in older adults is needed before a large clinical trial can be proposed. Therefore, our study aims to address the feasibility of a combined exercise intervention that older adults find acceptable and to which they will adhere.

Study Purpose

This study is exploring if it is reasonable and achievable for older adults (≥65 years old) with elevated blood pressure or stage I hypertension to engage in a unique exercise intervention combining isometric handgrip exercise (3-days/week) and walking 6000-8000 steps/day) to lower 24-hour blood pressure. Importantly, all participants who volunteer will be assigned to the exercise intervention group.

Participate in the Study

COULD THIS STUDY BE RIGHT FOR YOU?

  • You are 65 years or older
  • You have elevated blood pressure or have been diagnosed with stage 1 hypertension
  • Are NOT currently active on a regular basis (less than 2 days/week of planned activity)

WHAT PARTICIPANTS CAN EXPECT

The research study lasts about 8 weeks and includes:

  • Questionnaires and surveys for you to complete during in-person visits;
  • An initial in-person visit to our research center to learn more about the study and complete additional questionnaires about general health and your daily feelings of fatigue, resting blood pressure in both arms, height, and weight, a 24-hour blood pressure assessment, and to provide you with study materials and devices used in the study;
  • Participation in 8-weeks of a combined exercise intervention which includes tracking your daily steps with a pedometer (6000-8000/day) + 3-days per week of isometric handgrip exercise. We will also ask you to participate in once per week one-on-one Zoom sessions with investigators during the 8-week program.
    • *During the 8-week program: a halfway point (week 4) in-person follow-up with investigators to complete resting and 24-hour blood pressure assessments and questionnaires to evaluate your progress.
  • Two final visits to the research lab to complete resting blood pressure in both arms, a final 24-hour blood pressure measure and post-intervention questionnaires and surveys after the 8 weeks.

IsoWalk is currently recruiting participants!

For more about this study or if you are interested in getting involved, please visit the IsoWalk projects page OR our Pitt+Me study website. Or you can communicate directly with members of the research team via email: isowalk@pitt.edu or by phone: (412) 383-3576.